Table 1. Study population demographic and clinical measures, cognitive scores and brain MRI characteristics (data shown as mean ± SD or as number of cases and percentage n (%)).
| Demographic and clinical measures | (N = 142) |
| Age, years | 65.9±9.5 |
| Education, years | 13.6±3.7 |
| Admission NIHSS | 2.5±3.0 |
| Systolic blood pressure mmHg | 140±20 |
| Gender, male, n (%) | 76 (53.1%) |
| Risk factors | |
| Hypertension, n (%) | 82 (57.3%) |
| Diabetes mellitus, n (%) | 29 (20.3%) |
| Dyslipidemia, n (%) | 81 (56.6%) |
| History of heart disease, n (%) | 22 (15.5%) |
| Atrial fibrillation n (%) | 13 (9.2%) |
| Smoking, n (%) | 26 (18.1%) |
| Body mass index >25, n (%) | 95 (66.3%) |
| Infarct Location | |
| No infarct | 50 (36%) |
| Cortical infarct | 30 (21%) |
| Sub-cortical infarct | 48 (33%) |
| Subtentorial infarct | 14 (10%) |
| Cognitive score (1 year follow-up) | |
| Global cognitive score | 96.7±12.4 |
| Memory score | 97.9±15.7 |
| Executive function score | 98.1±12.0 |
| Verbal function score | 90.2±22.8 |
| Visual spatial score | 98.5±18.6 |
| Attention score | 98.8±13.2 |
| Brain MRI characteristics | |
| Ischemic lesions volume, mm3 | 4949±13741 |
| ICV, mm3 | 1348527±141014 |
| Relative ischemic lesions volume, % of ICV | 0.366±1.04 |
| WML volume, mm3 | 18203±17727 |
| Relative WML, % of ICV | 1.3±1.3 |
| WML FA values, arbitrary units | 0.29±0.05 |
| WML MD values, mm2/sec | 0.0012±0.0001 |
| WML eigenvalue1 (Da), mm2/sec | 0.0016±0.00018 |
| WML Dr values, mm2/sec | 0.0010±0.00017 |
| WML eigenvalue2, mm2/sec | 0.0011±0.00017 |
| WML eigenvalue3, mm2/sec | 0.00097±0.00017 |
| NAWM FA values, arbitrary units | 0.40±0.01 |
| NAWM MD values, mm2/sec | 0.0008±0.00003 |
| NAWM eigenvalue1 (Da) values, mm2/sec | 0.0012±0.00005 |
| NAWM Dr values, mm2/sec | 0.0006±0.00004 |
| NAWM eigenvalue2, mm2/sec | 0.00078±0.00004 |
| NAWM eigenvalue3, mm2/sec | 0.00055±0.00004 |
Abbreviations: NIHSS, National Institutes of Health Stroke Scale; ICV, intracranial volume; WML, white matter lesions; FA, fractional anisotropy; MD, mean diffusivity; Dr, radial diffusivity; Da, axial diffusivity; NAWM, normal-appearing white matter.