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. 2014 Aug 25;9(8):e105737. doi: 10.1371/journal.pone.0105737

Table 1. Characterisation of the non-stimulated CNS cell cultures and following an inflammatory stimulus.

Non-stimulated LPS+IFN-γ stimulation Fold change
% O4+ cells WT 20.94±0.09 15.87±0.22 0.76±0.01
Hsp70.1 KO 15.09±5.43 10.09±3.23 0.67±0.03
% MBP+ cells WT 4.37±0.75 2.85±0.07 0.67±0.13
Hsp70.1 KO 2.93±0.13 1.15±0.97 0.39±0.32
% Casp3+ cells WT 1.80±0.63 4.01±1.66 2.51±0.86
Hsp70.1 KO 2.31±0.58 3.57±0.63 1.60±0.33
% O4+Casp3+ cells WT 0.51±0.43 2.19± 0.28 6.45±4.96
Hsp70.1 KO 0.97±0.36 1.64± 0.58 1.70±0.13

The percentage of O4+, MBP+ and Casp3+ cells from the total number of cells of non-stimulated or LPS plus IFN-γ-stimulated cultures from wild-type (WT) and Hsp70.1 knock-out (KO) mice after 24 h. Fold change induced by inflammatory stimulus of each population was calculated referred to matched non-stimulated cultures. The results were expressed as the mean±SD.