Table 2. Differences in transcriptional regulation between NTAL KO and WT cells.

Biological processes different in NTAL KO vs WT cells			Molecular functions different in NTAL KO vs WT cells
Biological process	Genes in non-activated cells	Genes in activated cells	Molecular function	Genes in non-activated cells	Genes in activated cells
metabolic processes	24	17	nucleotide binding	38	41
biosythetic processes	15	2	protein binding	21	31
transcription and its regulation	12	15	DNA binding	14	20
mRNA/rRNA processing and translation	11	2	catalytic activity	12	5
transport	11	3	RNA binding	8	1
protein phosphorylation and dephosphorylation	8	9	nucleic acid binding	7	5
cell cycle	7	14	receptor and signal transducer activity	6	3
ATP catabolic process	5	5	binding	5	5
DNA replication	5	6	magnesium ion binding	4	0
apoptosis	4	5	phosphoprotein phosphatase activity	4	2
signal transduction	4	6	chromatin binding	2	0
mitosis	3	9	peptidyl-prolyl cis-trans isomerase activity	2	1
DNA repair	3	7	actin binding	2	3
protein folding	3	1	serine-type endopeptidase inhibitor activity	2	1
microtubule organization and depolymerization	1	4	iron ion binding	2	1
cell proliferation	0	4	calcium ion binding	2	0
ubiquitin-dependent processes	0	4	structural molecule activity	1	2
cytokinesis and cytokine production	0	4	ubiquitin thiolesterase activity	0	2
other process	51	31	other function	44	28
unknown process	42	46	unknown function	33	43
total number of genes	209	194	total number of genes	209	194