Table 3. Effects of independent variables on the rate of stricture formation before and after controlling for confounding factors.

Characteristic		Stricture	No Stricture	Odds Ratio (95% CI)	P value	Adjusted odds ratio (95% CI)	Adjusted P value
Prophylactic Anti-reflux Medication	Yes	24	33	2.727 (0.73–12.56)	0.0995	2.60 (0.71–9.46)	0.147
	No	4	15
Prematurity (<37 weeks) #	Yes	4	19	0.265 (0.059–0.97)	0.0256	0.32 (0.09–1.13)	0.079
	No	23	29
Delayed anastomosis	≥61.5 hours	10	9	2.407 (0.73–7.94)	0.0995	2.69 (0.82–8.82)	0.101
	<61.5 hours	18	39
Type of first operation	TOF ligation only	4	2	3.83 (0.50–44.39)	0.1146	*	*
	Primary anastamosis	24	46
Recurrent fistula or anastomotic leak	Yes	4	2	3.83 (0.50–44.39)	0.1146	*	*
	No	24	46
Low birth weight	<2500 g	8	21	0.514 (0.16–1.54)	0.1889	*	*
	≥2500 g	20	27
Antenatal diagnosis	Yes	5	4	2.39 (0.46–13.13)	0.2151	*	*
	No	23	44
GOR diagnosed	Yes	18	24	1.8 (0.63–5.30)	0.2270	*	*
	No	10	24
Delayed initiation of oral feeding #	≥12 days	9	10	1.91 (0.56–6.32)	0.2338	*	*
	<12 days	17	36
Trainee primary operator	Yes	3	10	0.456 (0.07–2.03)	0.2584	*	*
	No	25	38
Suture material #	Absorbable	24	45	0.53 (0.07–4.33)	0.4564	*	*
	Non-absorbable	3	3
Sex	Male	17	25	1.42 (0.50–4.11)	0.4654	*	*
	Female	11	23
Delayed presentation	≥18 hours	9	12	1.42 (0.44–4.45)	0.5018	*	*
	<18 hours	19	36
Ventilated post-operatively	Yes	27	45	1.8 (0.14–97.93)	0.6139	*	*
	No	1	3
Associated anomalies	Yes	16	25	1.23 (0.43–3.50)	0.6695	*	*
	No	12	23
Ethnicity #	White British	21	39	0.81 (0.22–3.17)	0.7182	*	*
	Other	6	9

*Variable did not have a statistically significant effect on the fit of the model and was therefore excluded from the multivariate model.

^#Information on Variable Missing for One Or More Infant.