Table 3. Shows significant gray matter atrophy in MCI converters in comparison to MCI non-converters.
L/R bAnatomical topography | Cl (k) | BA | Peak levela | T.c | |||
T-value | Z | x | y | z | |||
L Inferior Parietal Lobule | 147 | 40 | 5.38 | 4.32 | −41 | −58 | 43 |
L Lentiform Nucleus, Putamen | 3752 | --- | 5.38 | 4.32 | −27 | 5 | 7 |
L Middle Temporal Gyrus | 1187 | 21 | 5.34 | 4.29 | −51 | −30 | 1 |
L Middle Frontal Gyrus | 164 | 6 | 5.05 | 4.13 | −36 | 12 | 48 |
L Frontal Lobe, Precentral Gyrus | 285 | 9 | 4.73 | 3.94 | −36 | 12 | 40 |
L Medial Frontal Gyrus | 150 | 10 | 4.62 | 3.87 | −15 | 59 | 6 |
R Superior Frontal Gyrus | 608 | 8 | 4.62 | 3.87 | 8 | 18 | 54 |
R Medial Frontal Gyrus | 527 | 9 | 4.41 | 3.74 | 5 | 36 | 33 |
R Middle Frontal Gyrus | 137 | 6 | 4.19 | 3.60 | 30 | 18 | 52 |
L Frontal Lobe, Precentral Gyrus | 119 | 44 | 4.05 | 3.50 | −47 | 8 | 9 |
L Sub-lobar, Insula | 195 | --- | 4.15 | 3.57 | −45 | −1 | 1 |
R Parahippocampal Gyrus | 115 | 19 | 4.34 | 3.69 | 33 | −54 | −6 |
independent t-test,
L = left, R = right, Cluster level (Cl), Brodmann Area (BA), Talairach coordinates (T.c), Significant clusters (k≥100 voxels/p<0.001 uncorr.a) showing gray matter loss in MCI converters (n = 13) in comparison to MCI non-converters (n = 14) using analysis of T1-weighted images corrected for age.