Table 4. Shows group differences of GM atrophy of MCI converters in comparison to healthy controls.
L/R bAnatomical topography | Cl (k) | BA | Peak levela | T.c | |||
T-value | Z | x | y | z | |||
L Middle Temporal Gyrus | 1560 | 21 | 6.35 | 5.21 | −59 | −24 | −8 |
R Temporal Lobe, Fusiform Gyrus | 468 | 19 | 4.80 | 4.22 | 47 | −67 | −9 |
R Inferior Temporal Gyrus | 386 | 20 | 4.06 | 3.68 | 63 | −25 | −24 |
R Superior Temporal Gyrus | 197 | 38 | 3.98 | 3.61 | 44 | 26 | −23 |
R Superior Temporal Gyrus | 561 | 38 | 3.84 | 3.51 | 48 | 12 | −29 |
R Medial Frontal Gyrus | 1747 | 10 | 4.52 | 4.02 | 6 | 50 | 10 |
R Inferior Frontal Gyrus | 135 | 11 | 4.09 | 3.70 | 24 | 32 | −17 |
R Inferior Frontal Gyrus | 199 | 9 | 4.04 | 3.66 | 48 | 8 | 24 |
R Superior Frontal Gyrus | 1063 | 6 | 5.09 | 4.42 | 8 | 20 | 57 |
R Occipital Lobe, Lingual Gyrus | 398 | 18 | 3.87 | 3.53 | 15 | −67 | −5 |
independent t-test,
L = left, R = right, Cluster level (Cl), Brodmann Area (BA), Talairach coordinates (T.c), Significant clusters (k≥100 voxels/p<0.001 uncorr.a) showing gray matter loss in MCI converters (n = 13) in comparison to healthy controls (n = 28) using analysis of T1-weighted images corrected for age.