Table 1.
Case 1 | Case 2 | Case 3 | |
---|---|---|---|
Ages | 78 | 78 | 70 |
Gender | Male | Female | Female |
Presenting symptoms and signs | Headache, left sided weakness, dysarthria | Headache, vertigo, nausea, dysmetria, ataxia | Headache, nuchal rigidity, fever, dysarthria, dysmetria |
Last epidural injection prior to admission | 2 weeks | 2 weeks | One month |
| |||
CSF results: | N/A | ||
Nucleated cells (per μL) | 2,974 | 1485 | |
Polymorphonuclear cells (%) | 93 | 53 | |
Lymphocytes (%) | 4 | 36 | |
Red cells (per μL) | 468 | 6 | |
Protein (mg/dL) | 245 | 290 | |
Glucose mg/dL) | 28 | 12 | |
Gram stain | No bacteria | No bacteria | |
Bacterial culture | No growth | No growth | |
CDCa Exserohilum PCR | Positive | Negative | |
AFB culture | No growth | No growth | |
Aspergillus antigen index | Negative | Negative | |
Methenamine silver stain | N/A | Negative | |
| |||
Initial Imaging results | Pontine/midbrain small vessel ischemic stroke | Pontine, cerebellar ischemic strokes suggesting large vessel etiology | Thalamic/internal capsule small vessel ischemic stroke |
| |||
Pathologic/Autopsy results | Exserohilum rostratum | Fungus with hyphal features | N/A |
Centers for Disease Control