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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Neurobiol Learn Mem. 2014 May 10;114:70–80. doi: 10.1016/j.nlm.2014.04.012

Fig. 8.

Fig. 8

Expression of c-Fos and activity-regulated cytoskeleton-associated protein (Arc) in the CA1 region and entorhinal cortex. Seven- to nine-week old CD-1 wild-type or EAAT3 knockout mice were subjected to the fear conditioning stimuli. Their CA1 regions (panels A and C) and entorhinal cortices (panels B and D) were harvested before the stimuli, or 30 min or 180 min after the stimuli for Western blotting of c-Fos (panels A and B) and Arc (panels C and D). Total cellular protein was used for the assay. A representative Western blot is shown on the top of each panel and a graphic presentation of the c-Fos and Arc protein abundance quantified by integrating the volume of c-Fos autoradiogram bands from 5 to 16 mice for each experimental condition is shown in the bottom of each panel. Values in graphs are means ± SEM. *P < 0.05 compared with wild-type mice; ^P < 0.05 compared with the corresponding value at time 0. EAAT3 −/− : glutamate transporter type 3 knockout.