Table 1.
Characteristics of patients with low and normal total testosterone levels
| Factor | Low (n=1288) |
Normal (n=1131) |
|---|---|---|
| Age (y) | 67.5±11.3 | 67.0±11.3 |
| African American | 128(9.9) | 140(12.4) |
| eGFR at inception (mL/min/1.73m2)* | 48.4±9.8 | 49.8±9.1 |
| eGFR category* | ||
| 45–59 mL/min/1.73m2 | 906(70.3) | 870(76.9) |
| 30–44 mL/min/1.73m2 | 303(23.5) | 208(18.4) |
| 15–29 mL/min/1.73m2 | 79(6.1) | 53(4.7) |
| BMI (kg/m2)* | 30.3±5.7 | 28.4±5.0 |
| BMI category* | ||
| <18.5 kg/m2 | 3(0.23) | 7(0.62) |
| 18.5–24.9 kg/m2 | 189(14.7) | 268(23.7) |
| 25–29.9 kg/m2 | 496(38.5) | 501(44.3) |
| ≥30 kg/m2 | 588(45.7) | 343(30.3) |
| Missing | 12(0.93) | 12(1.1) |
| Smoking Status | ||
| No | 1144(88.8) | 979(86.6) |
| Yes | 81(6.3) | 95(8.4) |
| Missing | 63(4.9) | 57(5.0) |
| Diabetes * | 459(35.6) | 285(25.2) |
| Hypertension | 1206(93.6) | 1037(91.7) |
| Cerebrovascular disease * | 150(11.6) | 102(9.0) |
| Malignancy | 367(28.5) | 306(27.1) |
| Coronary artery disease | 390(30.3) | 324(28.6) |
| Chronic heart failure | 178(13.8) | 152(13.4) |
| Hyperlipidemia | 1102(85.6) | 953(84.3) |
| Lowest testosterone before inception (ng/dL) | 253.5[199.0–303.0] | 478.0[405.0–562.0] |
| Albumin (g/dL)^ | 4.2±0.40 | 4.2±0.41 |
Note: Values for categorical variables are given as number (percentage) with chi-square test; values for continuous variables are given as mean ± standard deviation with t-test or median [interquartile range] with Kruskal-Wallis test.
BMI: body mass index, eGFR, estimated glomerular filtration rate
^
Albumin data missing for 207 (9%) patients
*
Significantly different between patients with low and normal testosterone.