Table 1.
Clinical characteristics of study patients.
| Control (n=18) | Severe Preeclampsia (n=15) | p valueb | |
|---|---|---|---|
| Age (years) | 33.8 ± 4.5 (25-41) | 28.5 ± 6.6 (21-41) | 0.01 |
| BMI at delivery | 31.4 ± 6.7 (23.2-48.6) (n=17) | 38.2 ± 9.2 (25.6-54.0) | 0.03 |
| Gravidity | 3 (3-4) | 2 (1-3) | 0.02 |
| Parity | 1 (1-2) | 0 (0-2) | 0.14 |
| Ethnicity | |||
| White | 12 | 7 | |
| Black | 3 | 8 | 0.99 |
| Asian | 3 | 0 | 0.07 |
| Gestational age at delivery (weeks) | 38.7 ± 0.8 (37.2-39.7) | 33.9 ± 4.2 (27.4-39.9) | <0.001 |
| Labor status | |||
| Not in labor | 14 | 10 | |
| In labor | 4 | 5 | 0.48 |
| Mode of delivery | |||
| Cesarean | 16 | 12 | |
| Vaginal | 2 | 3 | 0.48 |
| Blood pressure | |||
| Systolic (mm Hg) | 115.9 ± 13.1 (110-148) | 164.7 ± 13.8 (143-186) | <0.001 |
| Diastolic (mm Hg) | 72.5 ± 9.1 (57-92) | 103.9 ± 8.4 (90-115) | <0.001 |
| Proteinuria | |||
| Protein dip | 0.28 ± 0.75 (0-3) | 2.6 ± 1.1 (1-4) (n=10) | <0.001 |
| Past medical history | |||
| Hypertension | 0 | 7 | |
| Pregnancy-related morbidity | |||
| Gestational diabetes | 1 | 4 | 0.12 |
| HELLP syndrome | 0 | 3 | |
| Chorioamnionitis | 0 | 1 | |
| Birthweight (grams) | 3488 ± 393 (2980-4710) | 2309 ± 1191 (590-4850) | <0.001 |
| Fetal growth restriction | 0 | 3 | |
| Freezer storage time (days) | 426.1 ± 295.8 (133-1024) | 837.2 ± 322.0 (155-1099) | <0.001 |
Data are presented as mean ± standard deviation (range). Gravidity and parity are presented as median (interquartile range). The n is provided if different from the group n due to unavailable data.
BMI, body mass index; HELLP, hemolysis, elevated liver enzymes, low platelets.
a
Standard diagnostic criteria for severe preeclampsia were used: a systolic blood pressure ≥160 mm Hg and/or a diastolic blood pressure ≥110 mm Hg and proteinuria >500 mg/24 hours.
b
Student's t-test for continuous variables, F test for categorical variables.