Skip to main content
. Author manuscript; available in PMC: 2015 Oct 7.
Published in final edited form as: Chem Soc Rev. 2014 Oct 7;43(19):6750–6764. doi: 10.1039/c3cs60459d

Figure 4.

Figure 4

A cartoon representing the constructions of the full-length Aβ1-42 peptides. The N-terminal truncated Aβ monomers are U-shape with the β-strand-turn-β-strand motif. The missing N-terminal portions of these NMR-derived Aβ peptides are recovered with the coordinates from the solution structure of Aβ1-16 (pdb id: 1ZE7).47 By covalently connecting the N-terminal to the truncated Aβ peptides, two Aβ1-42 conformers (conformer 1 and 2) with different turns can be generated.