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. Author manuscript; available in PMC: 2015 Oct 7.
Published in final edited form as: Chem Soc Rev. 2014 Oct 7;43(19):6750–6764. doi: 10.1039/c3cs60459d

Figure 9.

Figure 9

Aβ mutant channels/barrels in the lipid bilayers. (A) Simulated channel/barrel structures with an embedded pore structure for the p3-F19P (from the truncated Aβ17-42) mutant channel (left panel, from Jang et al., 2010,36 reprinted with permission) and for the conformer 1 and the conformer 2 F19P (from the full-length Aβ1-42) mutant barrels (middle and right panels, from Connelly et al., 2012,78 reprinted with permission). (B) Simulated barrel structures with an embedded pore structure for the conformer 1 and the conformer 2 F20C (from the full-length Aβ1-42) mutant barrels (from Connelly et al., 2012,78 reprinted with permission).