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. 2014 Jul 29;5(7):609–624. doi: 10.7150/jca.9002

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Effects of PQQ on cell cycle regulation in A549 and Neuro-2A cells. Flow cytometry analysis of cell cycle distribution of A549 and Neuro-2A cells. The 2 cell lines were treated with PQQ at the indicated concentrations for 24h. Effects of PQQ on cell cycle were investigated using PI (Propidium Iodide) staining subjected to flow cytometry (panels A and C). The peaks from left to right represent sub-G0/G1 phase, G0/G1 phase, S phase and G₂M phase respectively. Represent cells in different phases from three independent experiments (panels B and D).