Table 1.
Vascular remodeling of the carotid artery and aorta of normal and streptozotocin-induced type I diabetic rats
| Aortic arch | Carotid artery | |||
|---|---|---|---|---|
| Sham (N = 6) | STZ (N = 6) | Sham (N = 4-5) | STZ (N = 4-5) | |
| Total density (cells/mm2) | 3114 ± 204 | 2693 ± 284 | 2869 ± 223 | 2710 ± 237 |
| PHH3(+) (cells/mm2) | 1032 ± 201 | 137 ± 28* | 797 ± 124 | 416 ± 108* |
| PHH3(+)/Nestin(-) (cells/mm2) | 645 ± 131 | 84 ± 18* | 430 ± 73 | 273 ± 87* |
| Nestin(+) (cells/mm2) | 641 ± 89 | 385 ± 48* | 590 ± 72 | 355 ± 64* |
| PHH3(+)/Nestin(+) (cells/mm2) | 387 ± 77 | 52 ± 15* | 368 ± 62 | 143 ± 36* |
STZ indicates streptozotocin-induced diabetic rats, data are presented as mean ± SEM, analyzed by unpaired t-test, (*) represents P < 0.05 versus sham and (N) number of rats examined.