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Best overall response (Response Evaluation Criteria in Solid Tumors)
| Response, n | AUY922 dose (mg/m2) | |||||||
|---|---|---|---|---|---|---|---|---|
| 8 (n = 3) | 16 (n = 3) | 22 (n = 3) | 28 (n = 5) | 40 (n = 3) | 54 (n = 6) | 70 (n = 8) | Total, n (%) (N = 31) | |
| Complete response | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Partial response | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 (3) |
| Stable disease | 1 | 1 | 0 | 1 | 1 | 1 | 5 | 10 (32) |
| Progressive disease | 2 | 2 | 3 | 4 | 2 | 3 | 3 | 19 (61) |
| Unknown | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 (3) |
| Overall response rate (CR + PR) | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 (3) |
| Disease control rate (CR + PR + SD) | 1 | 1 | 0 | 1 | 1 | 2 | 5 | 11 (36) |
