Table 4. SNPs in the coding region of bovine PRNP detected in this study.
| Countries | Cattle species or breeds (heads) | Polymorphic nucleotide positions (nucleotide mutaions)a) | |||||
|---|---|---|---|---|---|---|---|
| Vietnam | Vietnamese local cattle (24) | 8 (A to C) | 69 (C to T) | 75 (G to A) | 108 (T to A) | 126 (A to G) | 234 (G to A) |
| 357 (C to T) | 461 (G to A) | 555 (C to T) | 630 (C to T) | 675 (C to T) | 678 (T to C) | ||
| Indonesia | Sumatra Utara local cattle (2), | 69 (C to T) | 108 (T to G) | 126 (A to G) | 234 (G to A) | 267 (T to A) | 555 (C to T) |
| Peranakan Ongole (3), Unkown (4) | 630 (C to T) | 678 (T to C) | 783 (C to T) | ||||
| Kalimantan Selatan local cattle (11) | 8 (A to C) | 108 (T to G, T to A) | 126 (A to G) | 234 (G to A) | 267 (T to A) | 461 (G to A) | |
| 554 (A to G) | 555 (C to T) | 678 (T to C) | 783 (C to T) | ||||
| Bali cattle (34) | 108 (T to G) | 126 (A to G) | 234 (G to A) | 267 (T to A) | 461 (G to A) | 554 (A to G) | |
| 555 (C to T) | 630 (C to T) | 678 (T to C) | 783 (C to T) | ||||
| Thailand | Thai local cattle (7) | 108 (T to A) | 126 (A to G) | 234 (G to A) | 461 (G to A) | 555 (C to T) | 630 (C to T) |
| 675 (C to T) | 678 (T to C) | ||||||
a) Bold nucleotide positions are predicted to result in amino acid replacements. All others represent synonymous mutation. Amino acid replacements provided by SNPs are as follows: 8 (A to C) (K3T), 461 (G to A) (S154N) and 554 (A to G) (N185S). Nucleotide positions and mutations underlined have not yet been reported for domestic cattle. Numbering was derived from the six-octapeptide cattle allele. Nucleotide positions refer to GenBank AJ298878.