Table 2. Results of meta-analysis for FEN1 -69G>A and 4150G>T polymorphisms and cancer risk.

Polymorphism	Type	Allele model		Homozygous model		Heterozygous model		Dominant model		Recessive model
		A vs. G		AA vs. GG		AG vs. GG		(AA+AG) vs. GG		AA vs. (AG+GG)
		OR (95%CI)	PH	OR (95%CI)	PH	OR (95%CI)	PH	OR (95%CI)	PH	OR (95%CI)	PH
-69G>A	Total	0.73 (0.69–0.77)	0.20	0.54 (0.48–0.61)	0.31	0.76 (0.70–0.82)	0.39	0.70 (0.65–0.75)	0.26	0.62 (0.56–0.69)	0.51
	DSC	0.72 (0.66–0.79)	0.99	0.50 (0.41–0.61)	0.96	0.80 (0.70–0.91)	0.99	0.71 (0.63–0.81)	1.00	0.56 (0.47–0.68)	0.94
	Other	0.72 (0.61–0.84)	0.02	0.56 (0.49–0.65)	0.05	0.74 (0.67–0.82)	0.07	0.67 (0.55–0.81)	0.03	0.65 (0.57–0.75)	0.21
		T vs. G		TT vs. GG		TG vs. GG		(TT+TG) vs. GG		TT vs. (TG+GG)
		OR (95%CI)	PH	OR (95%CI)	PH	OR (95%CI)	PH	OR (95%CI)	PH	OR (95%CI)	PH
4150G>T	Total	0.77 (0.73–0.81)	0.19	0.59 (0.53–0.67)	0.37	0.79 (0.73–0.86)	0.16	0.74 (0.68–0.79)	0.13	0.67 (0.60–0.75)	0.61
	DSC	0.76 (0.69–0.83)	0.95	0.54 (0.44–0.66)	0.98	0.83 (0.73–0.95)	0.82	0.75 (0.66–0.86)	0.87	0.60 (0.50–0.72)	0.98
	Other	0.75 (0.64–0.87)	0.02	0.62 (0.54–0.72)	0.09	0.74 (0.60–0.91)	0.02	0.69 (0.56–0.86)	0.01	0.71 (0.63–0.81)	0.40

Allele model (A vs. G): (AA*2+GA) vs. (GG*2+GA); DSC: Digestive system cancer; P_H: P value for the heterogeneity test.