. 2014 Aug 26;4:6183. doi: 10.1038/srep06183

Table 2. Results of meta-analysis for FEN1 -69G>A and 4150G>T polymorphisms and cancer risk.

Polymorphism	Type	Allele model		Homozygous model		Heterozygous model		Dominant model		Recessive model
		A vs. G		AA vs. GG		AG vs. GG		(AA+AG) vs. GG		AA vs. (AG+GG)
		OR (95%CI)	P_H	OR (95%CI)	P_H	OR (95%CI)	P_H	OR (95%CI)	P_H	OR (95%CI)	P_H
-69G>A	Total	0.73 (0.69–0.77)	0.20	0.54 (0.48–0.61)	0.31	0.76 (0.70–0.82)	0.39	0.70 (0.65–0.75)	0.26	0.62 (0.56–0.69)	0.51
	DSC	0.72 (0.66–0.79)	0.99	0.50 (0.41–0.61)	0.96	0.80 (0.70–0.91)	0.99	0.71 (0.63–0.81)	1.00	0.56 (0.47–0.68)	0.94
	Other	0.72 (0.61–0.84)	0.02	0.56 (0.49–0.65)	0.05	0.74 (0.67–0.82)	0.07	0.67 (0.55–0.81)	0.03	0.65 (0.57–0.75)	0.21
		T vs. G		TT vs. GG		TG vs. GG		(TT+TG) vs. GG		TT vs. (TG+GG)
		OR (95%CI)	P_H	OR (95%CI)	P_H	OR (95%CI)	P_H	OR (95%CI)	P_H	OR (95%CI)	P_H
4150G>T	Total	0.77 (0.73–0.81)	0.19	0.59 (0.53–0.67)	0.37	0.79 (0.73–0.86)	0.16	0.74 (0.68–0.79)	0.13	0.67 (0.60–0.75)	0.61
	DSC	0.76 (0.69–0.83)	0.95	0.54 (0.44–0.66)	0.98	0.83 (0.73–0.95)	0.82	0.75 (0.66–0.86)	0.87	0.60 (0.50–0.72)	0.98
	Other	0.75 (0.64–0.87)	0.02	0.62 (0.54–0.72)	0.09	0.74 (0.60–0.91)	0.02	0.69 (0.56–0.86)	0.01	0.71 (0.63–0.81)	0.40

Allele model (A vs. G): (AA*2+GA) vs. (GG*2+GA); DSC: Digestive system cancer; P_H: P value for the heterogeneity test.