Table 3.
Hematologic effects of CoQ in PAH and healthy controls.
| Variable |
PAH |
Controls |
||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | 6 weeks | 12 weeks | P-value | Baseline | 6 weeks | 12 weeks | P-value | |
| Red blood cell (m/µl) | 5.2±0.2⁎ | 5.1 ± 0.2⁎ | 5.2 ± 0.2⁎ | 0.2 | 4.5±0.1 | 4.2±0.1 | 4.3±0.2 | 0.02 |
| Hematocrit (%) | 43.0±2.1 | 42.4 ±2.1⁎ | 43.8 ± 1.8⁎ | 0.2 | 39.9±1.0 | 37.9±0.7 | 38.6±1.3 | 0.02 |
| Hemoglobin (g/dl) | 14.1±0.9 | 14.0±0.9 | 14.6 ± 0.8 | 0.01 | 13.3±0.4 | 12.7±0.3 | 12.9±0.5 | 0.07 |
| Mean corpuscular volume (fl) | 82.1±2.4 | 83.0±2.2 | 83.5 ± 2.0 | 0.06 | 89.7±1.3 | 90.0±1.0 | 88.9±1.3 | 0.3 |
| Mean corpuscular hemoglobin (pg) | 26.8±1.1 | 27.3±0.9 | 27.8 ± 1.0 | 0.006 | 29.9±0.8 | 30.2±0.5 | 29.9±0.7 | 0.5 |
| Mean corpuscular hemoglobin content (g/dl) | 32.6±0.6 | 33.0±0.4 | 33.2 ± 0.7⁎ | 0.06 | 33.3±0.5 | 33.6±0.3 | 33.5±0.4 | 0.6 |
| Red blood cell distribution width (%) | 15.0±0.6⁎ | 15.1±0.7⁎ | 14.5 ± 0.5⁎ | 0.04 | 12.9±0.2 | 12.9±0.2 | 12.9±0.4 | 1.0 |
⁎
P≤0.05 PAH compared to controls for the corresponding time point in the study.