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Heterogeneity of tumor. mESC-WT- and mESC-MagA-derived tumors exhibited heterogeneity. Both tumors were positive for lineage-specific markers. Immunohistochemistry of brain sections reveal positive staining of each lineage-specific marker: HNF4a (mesoderm), Nestin and Musashi (ectoderm), and CD117 (endoderm). Scale bars: 100 µm.
