Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 27;4(10):972–989. doi: 10.7150/thno.9436

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

PMC Copyright notice

MRI of cell pellets and ICP-OES quantifications of iron in mESCs. (A) Color-coded R₂ map from multi-echo measurements of R₂ relaxation rate showed a significant increase in R₂ rate when mESC-MagA was treated with Dox and FC. The cell pellet of mESC-MagA Dox/FC showed significantly induced relaxivity (R₂) compared to mESC-WT with Dox/FC treatment (*P = 0.02, n = 3). Also, a significant increase in R₂ rate was observed when mESC-MagA Dox/FC was compared to mESC-MagA FC (*P = 0.002, n =3). (B) mESC-MagA Dox/FC showed the highest iron content compared to all other groups. Compared to mESC-WT Dox/FC, mESC-MagA Dox/FC had significantly higher iron content (*P = 0.041, n = 3). There was no significant change when mESC-WT Dox/FC was compared to mESC-WT None (P = 0.11, n = 3). All histogram data are means ± SEM. *P< 0.05 versus appropriate control by ANOVA.