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. 2014 Aug 1;4(10):1014–1025. doi: 10.7150/thno.9575

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Comparison of MRI-based detection (upper panels: CE-T1 MR images; 2^nd and 3^rd panels: MR Ktrans map, original and 2× / 4× enlarged) and rate constant α-change map (bottom panels; 2× / 4× enlarged) of FUS-induced BBB opening. (a) Control. (b) and (c) FUS exposure pressure of 0.5 MPa. (d) and (e) FUS exposure pressure of 0.7 MPa. Arrow: BBB-opening region.