Fig. 6.

The radius and ulna of Chkb^−/− mice contain fewer osteoclasts along the chondro-osseous junction. Bone sections from the radius (A, C) and ulna (B, D) of 7-day-old WT (A and B) and Chkb^−/− (C and D) mice were stained for the osteoclast marker, tartrate-resistant acid phosphatase (TRAP). Arrows show dark purple TRAP-positive cells. The number of TRAP-positive foci was quantified along the cartilage/bone interface (E, F). Data are means ± SEM from 3 littermates of each genotype; *: P < 0.05 compared to WT.