Figure 2. R121919 inhibits predator odor stress-induced increase in ASR amplitude 24–48 hours following stress.
Panel A depicts mean ± SEM startle amplitude in response to 90, 105 and 115 dB acoustic startle stimuli of control (white; n=8) and predator odor stressed (black; n=8) rats 24–48 hrs following stress. Panel B depicts mean ± SEM startle amplitude in response to 90, 105 and 115 dB acoustic startle stimuli of control (white; n=8) and predator odor stressed (black; n=8) rats 24–48 hrs following stress after systemic injection with 0 or 20 mg/kg R121919. $ denotes P<0.05 compared between intensities. # denotes P<0.05 main effect of stress. * denotes P<0.05 relative to control.
