Table 1. Hargreaves Intensity Response and Baseline.
Table depicts the mean paw withdrawal latency of rats (n=21; top panel) during light intensity- response tests to determine appropriate light intensity for pharmacology tests using the Hargreaves test of thermal nociception. A separate group of rats (n=31; bottom panel) were tested for baseline nociception with and without vehicle injection 60 minutes prior to testing over four days. There was no effect of vehicle injection on paw withdrawal latencies in unstressed rats.
Intensity Response | |||
25 AI | 50 AI | 75 AI | 99 AI |
18.77 ± 0.38 | 15.08 ± 0.43 | 8.79 ± 0.25 | 5.95 ± 0.21 |
Baseline (75 AI) | |||
No Injection | No Injection | Vehicle Injection | Vehicle Injection |
7.81 ± 0.30 | 8.18 ± 0.34 | 8.04 ± 0.24 | 8.20 ± 0.14 |