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Upper four panels: effects of 8-OH-DPAT, F13714, DOM and DPT alone or in combination with the 5-HT1A receptor antagonist WAY100635 or the 5-HT2A receptor antagonist MDL100907. See Fig 1 for other details. Bottom two panels: Schild plots constructed from the same data shown in the upper and middle panels. Abscissae, negative log of the dose of antagonist in moles per kilogram of body weight. Ordinates, log of the dose ratio – 1.
