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. 2014 Aug 26;8:84. doi: 10.3389/fnana.2014.00084

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Copyright © 2014 Afonso-Oramas, Cruz-Muros, Castro-Hernández, Salas-Hernández, Barroso-Chinea, García-Hernández, Lanciego and González-Hernández.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Biotinylated dextran amine (BDA) injection in the substantia nigra pars compacta (SNC) and ventral tegmental area (VTA) of the rat. (B–G) BDA-positive fibers emitting terminals in close apposition to striatal vessels, some of them in the form of individual axons (C,E,G), and others forming sparse plexuses (B,D,F). (H,I) Double labeling for BDA and vimentin (H) or GFAP (I) showing terminals abutted on striatal vessels and surrounding astrocytes (arrows in H and I). (D,G) Boxed areas in (B) and (E) respectively. The number at the bottom right in (A) indicates the distance from the interaural axis in millimeters. SNR, substantia nigra pars reticulata. v, vessel lumen. Bar in (A), 1 mm; in B, 400 μm; in (F) (for D and F), 150 μm; in (G), 100 μm; in (I) (for H and I), 100 μm.