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. 2014 Aug 26;8:84. doi: 10.3389/fnana.2014.00084

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Copyright © 2014 Afonso-Oramas, Cruz-Muros, Castro-Hernández, Salas-Hernández, Barroso-Chinea, García-Hernández, Lanciego and González-Hernández.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A,B) Immunohistochemistry for TH in the rat midbrain after sham (A) and 400 μg 6-OHDA (B) intracerebroventricular injection. (C,D) Immunofluorescence for THp19 in the striatum of sham (C) and 400 μg 6-OHDA (D) injected rats. One can see the decrease in the number of TH-positive midbrain cells after 6-OHDA injection (compare A and B), and that THp-19 striatal perivascular plexuses disappear after midbrain DA-cell degeneration (compare C and D). ac, anterior commissure; OT, olfactory tubercle; III, fibers of the third cranial nerve emerging in the surface of the ventral midbrain. Numbers at the bottom right indicate the distance from the interaural axis in millimeters. Bar in (B) (for A and B), 1 mm; in (D) (for C and D), 1 mm.