TABLE 4.

Final models in the stepwise multiple regression analyses identifying predictors of changes in the 3MS and total IWQOL among the intervention groups¹

	β	P
Final model of variables affecting change in 3MS
Diet group (multiple R = 0.503, P = 0.0003)
Change in ISI	0.468 ± 0.119	0.0001
Change in hs-CRP	−0.309 ± 0.119	0.01
Exercise group (multiple R = 0.489, P = 0.001)
Change in VO2peak	0.319 ± 0.121	0.01
Change in LE 1-RM strength	0.314 ± 0.131	0.01
Diet-exercise group (multiple R = 0.436, P = 0.002)
Change in LE 1-RM strength	0.272 ± 0.136	0.03
Change in VO2peak	0.257 ± 0.124	0.04
Final model of variables affecting change in total IWQOL
Diet group (R = 0.383, P = 0.002)
Change in body weight	−0.383 ± 0.123	0.002
Exercise group strength (R = 0.406, P = 0.002)
Change in LE 1-RM	0.406 ± 0.149	0.002
Diet-exercise group (multiple R = 0.564, P = 0.0001)
Change in body weight	−0.365 ± 0.128	0.004
Change in LE 1-RM strength	0.293 ± 0.116	0.01

¹Values are βs ± SEs. The samples for analysis were n = 23 for the control group, n = 23 for the diet group, n = 22 for the exercise group, and n = 25 for the diet-exercise group. Stepwise multiple linear regression analysis was used to identify which variables were independent contributors to the changes in the 3MS and total IWQOL in each intervention group. Variables entered into the model were as follows: change in body weight, change in visceral fat, change in ISI, change in hs-CRP, change in insulin-like growth factor I, change in VO_2peak, change in upper extremity 1-RM strength, change in LE 1-RM strength, and years of education (for 3MS only). hs-CRP, high-sensitivity C-reactive protein; ISI, insulin sensitivity index; IWQOL, Impact of Weight on Quality of Life–Lite; LE, lower extremity; VO_2peak, peak oxygen consumption; 1-RM, one-repetition maximum; 3MS, Modified Mini-Mental State Examination.