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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Am J Transplant. 2014 Apr 2;14(5):1084–1095. doi: 10.1111/ajt.12673

Figure 7.

Figure 7

Two-color immunochemistry analysis of tissues from GalTKO.hCD46 and control perfused pig lungs. Pig lung tissue collected at identical time points (10 min after initiation of perfusion) was stained for von Willebrand Factor (green), identifying endothelium, and C5b-9 (A), C4d (B) and CD41 (C) (red). (D) Immunochemistry findings scored as the extent of tissue deposition as indicated in methods. GalTKO.hCD46 lungs showed non-significantly reduced C4d (0.9±0.1 vs. GalTKO 1.3±0.2, p = 0.15) and CD41 deposition (1.1±0.2 vs. GalTKO 1.7±0.3, p = 0.19 vs. GalTKO) in lung biopsies collected at 10 min when compared to GalTKO or Wild Type lungs. C5b-9 IHC-score was similar in GalTKO.hCD46 and GalTKO lungs.