Figure 3.

Pathway proposed for production of the antifungal metabolite, 3, 4-dihydroxy-N-methyl-4-(4-oxochroman-2-yl) butanamide by PGPR2. Equation 1: Acetyl CoA carboxylase catalyzed the formation of malonyl CoA from acetyl CoA; Equation 2: Polyketide synthase catalyzed the formation of hexa keto compound by condensation of a molecule of acetyl CoA with five molecules of malonyl CoA; Equation 3: The hexa keto compound undergoes cyclization and condensation reactions to form different chromanone intermediates.