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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Behav Brain Res. 2014 Jul 5;272:209–217. doi: 10.1016/j.bbr.2014.06.054

Fig. 2.

Fig. 2

Illustration of the group-level difference of the intrinsic hippocampus functional network between the HD and the CN groups. The bright color illustrates brain regions with higher connectivity strength in the HD group while the blue color indicates lower connectivity strength, compared to the CN group. Significance level of this group-level difference was set at threshold p < 0.05, and p value of each voxel was obtained via a voxel-wise analysis of covariance (ANCOVA) with age, years of education and grey matter volume of each individual as covariance of non-interests. The results were corrected for multiple comparisons (3dClustSim, AFNI, α=0.05, p<0.05, cluster size > 2630mm3).

Abbreviations: DLPFC, dorsal lateral prefrontal cortex; Amy, amygdala; aTP, anterior temporal pole; PCC, posterior cingulate cortex; FFA, fusiform face area; DMPFC, dorsal medial prefrontal cortex; AG, angular gyrus; TPJ, temporal-parietal junction; dACC, dorsal anterior cingulate cortex; CN, control non-drug users; HD, heroin dependent subjects.