Table 2.

Group-level difference of the intrinsic hippocampus functional network between the HD and CN groups.

Brain Region	Side	BA	Cluster Size (mm3)	TLRC Coordinates (LPI)			Z Score
				x	y	z
Insula	R/L	13	90344	42	−7	13	4.08
Putamen	L/R			−24	10	6	3.59
Caudate	R/L			17	25	1	3.83
SCG/sACC	L/R	25		−2	17	−5	3.37
PCC	R/L	23/31		1	−35	35	3.17
Paracentral Lobule	L/R	31/5		−4	−25	47	3.42
AG/TPJ	R/L	39		35	−69	28	4.81
Precuneus	R/L	7		8	−54	38	3.81
Cuneus	R/L	18		9	−76	19	3.54
FFA	L	37	22296	−31	−47	−14	−4.06
MTG	L	22		−54	−47	−1	−3.98
Amygdala	L			−27	−8	−19	−3.54
aTP	L	38		−49	13	−17	−2.49
MTG	R	21	16672	65	−47	−10	−4.39
Amygdala	R			29	−4	−19	−2.62
aTP	R	38		45	18	−29	−2.98
Parahippocampal	R			32	−6	−30	−4.07
SFG	R		16328	29	57	22	−3.80
DLPFC	L/R	9		−27	43	38	−3.45
DMPFC	L/R	6/9		−3	39	39	−3.56
dACC	L/R	32		−4	35	29	−2.91
Lingual Gyrus	L	18	6240	−7	−79	−5	−3.54
MOG	L		2824	−25	−93	18	−3.75

Brain regions with positive z scores indicate significantly increased connectivity in the HD group compared to the CN group, while those with negative z scores indicate significantly decreased connectivity.

Abbreviations: BA, Brodmann area; SCG, subcallosal gyrus; sACC, subgenual dorsal anterior cingulate cortex; PCC, posterior cingulate cortex; AG, angular gyrus; TPJ, temporal-parietal junction; FFA, fusiform face area; MTG, middle temporal gyrus; aTP, anterior temporal pole; SFG, superior frontal gyrus; DLPFC, dorsal lateral prefrontal cortex; DMPFC, dorsal medial frontal gyrus; dACC, dorsal anterior cingulate cortex; MOG, middle occipital gyrus.