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. 2014 Aug 11;2014:624573. doi: 10.1155/2014/624573

Table 1.

Baseline characteristics and methodological quality of all included studies.

First author Year Country Ethnicity Sample size Gender (M/F) Age (years) Genotyping method SNP type HWE test (P value) NOS score
DN DM DN DM DN DM
Bonnefond [18] 2013 France Caucasian 1510 10581 917/593 6739/3842 64.3 ± 10.0 62.9 ± 10.1 TaqMan rs6921438 Y/X 0.953 7
60.4 ± 9.7 rs10738760 Y/X 0.095
Nikzamir [23] 2012 Iran Asian 255 235 129/126 106/129 59.6 ± 8.1 58.4 ± 7.6 PCR-RFLP rs2010963 G/C 0.401 6
Xiao [25] 2011 China Asian 111 105 63/48 55/50 63.4 ± 6.8 60.5 ± 6.2 PCR-ASA rs699947 G/A 0.118 7
Zhang [26] 2008 China Asian 102 92 54/48 44/48 59.9 ± 12.4 61.6 ± 10.4 PCR-RFLP rs3025039 C/T 0.063 7
Zhang [34] 2008 China Asian 173 123 63.7 ± 10.6 62.7 ± 9.9 PCR-RFLP rs3025039 C/T 0.581 7
Guo [30] 2008 China Asian 81 76 41/40 35/41 59.6 ± 10.9 57.1 ± 10.9 PCR-RFLP rs2010963 G/C 0.425 7
rs833061 C/T 0.172
Xue [33] 2007 China Asian 97 60 44/53 29/31 65.6 ± 11.6 PCR-RFLP −2549 D/I 0.368 8
McKnight [22] 2007 UK Caucasian 242 301 149/93 122/179 17.6 ± 9.0 15.9 ± 8.4 Pyrosequencing rs3025039 C/T 0.712 7
TaqMan rs699947 G/A 0.182
Pyrosequencing rs2010963 G/C 0.055
Buraczynska [24] 2007 Poland Caucasian 245 91 126/119 43/48 57.9 ± 10.7 56.9 ± 9.8 PCR-RFLP −2549 D/I 0.679 8
rs2010963 G/C 0.652
He [31] 2007 China Asian 129 120 64/65 56/64 62.9 ± 12.0 61.6 ± 15.3 PCR-RFLP rs3025039 C/T 0.661 7
Li [32] 2005 China Asian 104 112 58/54 50/48 62.1 ± 7.0 60.0 ± 6.8 PCR-RFLP rs2010963 G/C 0.511 8

DN: diabetic nephropathy; DM: diabetes mellitus; M: male; F: female; SNP: single nucleotide polymorphism; PCR-RFLP: polymerase chain reaction-restriction fragment length polymorphism; PCR-ASA: polymerase chain reaction-amplicon sequence analysis; HWE: Hardy-Weinberg equilibrium; NOS: the Newcastle-Ottawa Scale.