Table 2.

Medical costs and drug costs.

	LEN/DEX	BORT
Number of office visits	16	35
Rate (CPT 99212: office/outpatient  visits)	$41.45	$41.45
Evaluation and management   cost per patient	$663.20	$1450.75
Number of administrations	0	35
Rate (CPT 96409: chemo IV push  single drug)	$112.80	$112.80
Administration cost per patient	$0.00	$3948.00
Percentage of patients hydrated	0%	25%
Rate (CPT 96360: hydration IV  infusion init)	$57.08	$57.08
Hydration cost per patient	$0.00	$499.45
Number of CBCs	17	52
Rate (CPT 85025: complete CBC w/  auto diff WBC)	$43.00	$43.00
Lab tests cost per patient	$731.00	$2236.00
Herpes zoster (for Velcade  patients)a	NA	$21.78
DVT/PE (for Revlimid patients)b	$1713.05	NA
Prophylaxis costs per patient	$1713.05	$21.78
Total medical cost per patient	$3064.25	$8155.98
Treatment period (weeks)	52	27
Daily medical cost per patient	$8.42	$43.15
Drug cost per treatment day	$359.67	$1450.75
Treatment days/cycle days	21/28	4/21 then 4/35
Daily drug cost until progression	$270	$274

^aAssumes patients receive prophylaxis with generic acyclovir 400 mg/day. Cost based on WAC cost of $0.17 per 400 mg tablet×7 days per week for treatment with BORT^44,45.

^bCosts based on an enoxaparin AWP of $32.47 per 40 mg syringe and aspirin at $0.01 per tablet⁴⁵.

The herpes zoster prophylaxis costs may be conservative and may not reflect more extensive regimens provided to certain patients^{17,26,36,45,46}. DVT/PE, deep vein thrombosis/pulmonary embolism; LEN, lenalidomide; DEX, dexamethasone; CBC, complete blood cell count.