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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Mol Genet Metab. 2014 Jan 31;111(4):445–451. doi: 10.1016/j.ymgme.2014.01.012

Table 5.

Loss of standard score points in relation to 100 μmol/L increase in mean Phe and loss of standard score points in relation to 100 μmol/L increase in SD Phe after controlling for points lost in relation to mean Phe.

Time Period Matrix Reasoning n-back # nonresponses n-back # responses Go/No-Go errors



Mean Phe SD Phe Mean Phe SD Phe Mean Phe SD Phe Mean Phe SD Phe








Lifetime --- nc --- --- nc --- 3.2 ns --- nc ---
< 5 yrs. --- nc --- --- nc --- 4.4 ns --- nc ---
5.0 – 9.9 yrs. --- nc --- 2.4 8.4 --- nc --- 2.4 ns
≥ 10 yrs. 2.0 6.2 2.0 ns --- nc --- 3.1 ns

Note: nc = analysis not conducted due to lack of significant correlation between cognitive performance and mean Phe in earlier analyses; ns = not significant; IQ and Vocabulary are not included in the table because neither had significant correlations with mean Phe.