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. 2014 Jul 24;53(30):4881–4883. doi: 10.1021/bi500500h

Figure 2.

Figure 2

Competitive CXCR4 binding activity of DV1, SDF-1α, AMD3100, and IT1t in FITC-DV1- and 12G5 Ab-based competitive binding assays. (A) The competitive capacities of DV1 (blue asterisks) and SDF-1α (maroon times signs) in the FITC-DV1-based assay were comparable to those of DV1 (red circles) and SDF-1α (black triangles) in the 12G5 Ab-based assay, for binding CXCR4. (B) The competitive capacities of AMD3100 (black asterisks) and IT1t (red times signs) in the FITC-DV1-based assay were comparable to those of AMD3100 (black triangles) and IT1t (black diamonds) in the 12G5 Ab-based assay, for binding CXCR4. Means ± the standard deviation; n = 3 independent experiments.