Figure 1.
Chip layout of the PDMS/paper hybrid microfluidic device. (a) 3D illustration of the schematic of the chip layout. The chip consists of one top PDMS layer, one middle PDMS layer, and one glass slide for reagent delivery, LAMP reaction, and structure support, respectively. A chromatography paper disk is situated inside each LAMP zone to preload LAMP primers. (b) A photograph of the hybrid microfluidic device for infectious disease diagnosis. (c) A cross-section view of the LAMP zone illustrating the principle of the LAMP detection.