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. 2014 Jul 14;86(15):7978–7986. doi: 10.1021/ac5021694

Figure 2.

Figure 2

(a,b) Fluorescence images of preloaded Cy3-labeled primers (10.4 μM) in LAMP zones either with or without paper inside. When LAMP zones were dry, primers in paper-free LAMP zones accumulated on the edge of the LAMP zones, while primers in LAMP zones with paper inside were still uniformly distributed. (c) On-chip LAMP performance comparison between biochips with paper inside and without paper inside over a period of 2 months. Nucleic acid concentration of N. meningitidis LAMP products from LAMP zones with paper inside and without paper inside was measured to evaluate on-chip LAMP performance between these two different kinds of biochips. DNA concentration was normalized for convenient comparison.