Skip to main content
. 2014 Jul 2;11(8):2948–2953. doi: 10.1021/mp5002872

Table 1. 99mTc-Probestin Kidney Uptake (% ID/g) at 1 h Postinjection and Histopathology Results of UPII-SV40T Mouse Kidney Sectionsa.

          histopathology
      99mTc-probestin uptake
% renal pelvis that is occupied by tumor
% renal cortex that is occupied by tumor
mouse genotype age (wk) LK RK LK RK LK RK
1 transgenic 63 36.6 41.0 100 100 5 5
2 transgenic 57 39.0 48.3 100 100 1 1
3 transgenic 57 7.6 38.6 100 100 50 5
4 transgenic 25 63.1 65.4 100 30 5 0
5 transgenic 25 60.0 65.1 50 100 0 3
6 transgenic 80 57.1 71.3 0 0 0 0
7 transgenic 80 65.4 79.3 0 0 0 0
8 transgenic 50 36.0 38.2 100 100 5 10
9 transgenic 25 80.1 81.2 100 100 1 0
10 wild-type 60 56.5 56.6 0 0 0 0
11 wild-type 80 70.2 87.1 0 0 0 0
12 wild-type 25 69.6 78.6 0 0 0 0
kidneys 99mTc-probestin uptake
wild-type mouse kidneys (6 kidneys) 69.8 ± 12.1
transgenic mouse kidneys with no damage of renal cortex (7 kidneys) 68.5 ± 9.2
transgenic mouse kidneys with ≥1% damage of renal cortex (11 kidneys) 44.9 ± 19.1
a

Mouse 3 is female, and the other mice are male. LK: left kidney. RK: right kidney.