Figure 3. Efflux of cholestenone and cholesterol from HDFs to extracellular acceptors.

A) HDFs prelabeled with [¹⁴C]cholesterol were treated with coase (10 U/ml; 1 h), MBCD (0.5 mM; 5 min), or mock treated (ctrl). Efflux of radiolabeled lipids was analyzed after a 4 h chase in serum-free buffer containing B) ApoA-I (10 µg/ml); n = 4 or C) BSA (0.2%); n = 4–6. *P<0.05; **P<0.005; ***P<0.0005.