Figure 6. Delay in Proinflammatory Cytokine Production in TLR4^−/− Mice.

C57BL/6J or TLR4^−/− mice were infected with wild type or ΔmagA K. pneumoniae and eyes were assayed for KC, TNFα, or MIP-1α by ELISA. n≥5 eyes except for KC in C57BL/6J mice at 24 hours where n=3. Error bars represent standard deviation, *; p≤0.01, †; p<0.01 when values below the LOD were estimated by. $\frac{\mathit{LOD}}{\sqrt{2}}$.