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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Biomaterials. 2014 Jun 24;35(29):8348–8356. doi: 10.1016/j.biomaterials.2014.06.018

Figure 5. A proposed model of coordinated chemical and mechanical sensing in HMSCs.

Figure 5

Microtubules play a key role in integrating chemical and mechanical inputs to coordinate the β-AR agonist induced PKA activation and β-AR internalization, which forms a feedback loop.