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. 2014 Aug 26;9(8):e105253. doi: 10.1371/journal.pone.0105253

Table 3. The effects of Piroxicam on PRA, PRB and ESR1 protein and PR and ESR1 mRNA Relative Abundance in guinea pig uteri.

Vehicle						Piroxicam					Significance
Receptor	N	Mean	SD	Median	Range	N	Mean	SD	Median	Range	P
PRA protein	7	1.11	0.26	1.09	0.82–1.56	8	1.66	0.55	1.58	1.16–2.77	0.015 ^a
PRB protein	7	1.58	0.55	1.38	1.0–2.46	8	1.96	0.83	1.79	0.91–3.32	0.31^b
PR mRNA	7	0.81	0.30	0.86	0.21–1.16	8	0.77	0.66	0.66	0.22–2.18	0.64^a
ESR1 protein	7	0.28	0.17	0.29	0.13–0.61	8	0.38	0.33	0.23	0.13–0.99	0.86^a
ESR1 mRNA	7	1.60	0.61	1.01	0.55–2.29	8	1.20	0.24	1.26	0.75–1.50	0.13^b

Details of the treatments are described in the text.

^a

, Mann-Whitney test; ^b, two-sample t-test.

Significant difference is in bold. N: number of animals per group.