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. 2014 Aug 26;9(8):e105754. doi: 10.1371/journal.pone.0105754

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© 2014 Barbosa et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The agreement between methods using Bland-Altman analysis for the measurements of extracellular water volume (ECW) by sodium bromide dilution method (Br⁻), single frequency bioelectrical impedance analysis (BIA) or bioelectrical impedance spectroscopy (BIS) before and after 1 year of growth hormone replacement therapy (GHRT). The solid line represents the mean differences between the methods and the dashed lines represent the lower and upper 95% limits of agreement (±1.96 SD) for the measurements. Br⁻ vs BIA (A and B) and Br⁻ vs BIS (C and D); before (A and C) and after GHRT (B and D).