Table 1. Parameters associated with renal impairment and renal function.
| Sham group | Model group | |||
| Baseline | 2 weeks | Baseline | 2 weeks | |
| Lactic dehydrogenase (U/L) | 15.0±9.4 | 14.6±8.3 | 18.7±12.7 | 45.0±16.1a b |
| Lactic acid (mmol/L) | 1.4±0.7 | 1.1±0.4 | 1.9±0.9 | 1.2±0.4 |
| Creatinine (umol/L) | 32.8±8.5 | 37.9±6.2 | 36.2±3.9 | 45.8±1.8a b |
| Creatinine clearance (ml/min/kg) | 4.0±0.3 | 2.9±0.4c | ||
| Urea nitrogen (mmol/L) | 2.2±0.4 | 2.8±0.7 | 3.1±1.0 | 4.2±1.0a b |
| Sodion (mmol/L) | 148.7±2.6 | 151.6±1.1 | 148.4±3.1 | 149.0±3.2 |
| Potassium (mmol/L) | 5.1±0.4 | 4.7±0.1 | 4.5±0.5 | 4.6±0.3 |
a
p<0.05 vs. baseline of model group;
b
p<0.05 vs. 2 weeks of sham group;
c
P<0.05 vs. 2 weeks of sham group. (mean ± standard deviation, n = 5).