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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Ophthalmology. 2014 May 6;121(9):1818–1826. doi: 10.1016/j.ophtha.2014.03.020

Table 5.

Optic nerve parameters in 26 preterm infants when aged 31–36 weeks vs. 37–42 weeks PMA*

Parameters 31–36 weeks PMA
Mean (SD)
37–42 weeks PMA
Mean (SD)
Mean Difference Overall (SE)* % Change Overall Estimated Mean Difference per Week (μm) Estimated % Change per Week P-Value**
vDiscDiam (μm) 1254 (193) 1328 (137) 74 (28) 5.9% 16 1.3% 0.008***
vCupDiam (μm) 918 (219) 915 (267) −4 (21) −0.4% −1 −0.1% 0.431
vC:D 0.74 (0.16) 0.69 (0.17) −0.05 (0.02) −6.8% −0.01 −1.4% 0.015***
Cup Depth (μm) 432 (148) 461 (170) 28 (26) 6.5% 6 1.4% 0.858
*

Average weeks between imaging sessions = 4.7

**

Wilcoxon Rank Sums test, 1-tailed

***

Repeat analysis with cup offset 150 μm above the disc plane; p-values for vDiscDiam and vC:D changed to p=0.012 and p=0.053, respectively

vDiscDiam, vertical disc diameter; vCupDiam, vertical cup diameter; vC:D, vertical cup-to-disc ratio

SD, standard deviation; SE, standard error