Table 1.

Key distinguishing pathologic differences between CNL and aCML according to the 2008 WHO Classification.[1].

	Chronic neutrophilic leukemia	Atypical chronic myeloid leukemia
Blood
Immature granulocytesa	<10%	≥10%
Myeloblasts	<1%	<20%
Marrow
Granulocytic hyperplasia	Present	Present
Myeloblasts	<5%	<20%
Granulocytic dysplasia	Minimal/absent	Present
Megakaryocytic dysplasia	Absent	Present

^aPromyelocytes, myelocytes, and metamyelocytes.