Figure 12.

Response of the model to 1 kHz monolateral excitatory inputs with somatic inhibition. Inhibitory events precede excitatory events by 0.35 ms. Peak synaptic conductance is 10 mS/cm² for excitation and 4 mS/cm² for inhibition. A, Spatiotemporal profile of membrane potential. The ordinate represents the mediolateral or dendritic distance in micrometers, with 0 representing the soma. The abscissa is the time axis; it begins at 4 ms to show only the ongoing response. The black icon at left represents the dimensions of the neuron model. The resting membrane potential is −60 mV. B, Spatiotemporal profile of the simulated neurophonic; note the change in scale on the ordinate from A. The dashed black line at t = 6.3 ms indicates the time at which the spatial cross-sections in Figure 13 are taken. C, Spatiotemporal profile of the simulated neurophonic with mean value removed from every spatial location. This mimics the 10 Hz high pass filter imposed by data acquisition system in experiments of Mc Laughlin et al. (2010). D, Difference of simulated neurophonic responses with and without inhibition (i.e., the difference between Figs. 12C and 4C).