Table A2.
Association of TERT Promoter C228T Mutation With BRAF V600E Mutation in PTC
Tumor Type |
TERT C228T Mutation |
BRAF V600E Mutation |
OR | 95% CI | P | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
BRAF− |
BRAF+ |
TERT− |
TERT+ |
||||||||
No. | % | No. | % | No. | % | No. | % | ||||
All PTC | 26 of 313 | 8.3 | 35 of 194 | 18.0 | 159 of 446 | 35.7 | 35 of 61 | 57.4 | 2.43 | 1.40 to 4.21 | .001 |
CPTC | 19 of 219 | 8.7 | 28 of 164 | 17.1 | 136 of 336 | 40.5 | 28 of 47 | 59.6 | 2.17 | 1.16 to 4.06 | .013 |
Abbreviations: CPTC, conventional papillary thyroid cancer; PTC, papillary thyroid cancer.